1. T2* quantitation is a standard CMR technique for disease monitoring and guiding chelation therapy in cardiac iron- loading conditions
  2. Single breath-hold, multi-echo, T2* sequence (gradient echo or modified black blood sequence)
  3. Single mid-ventricular slice
  4. Single transaxial slice of the liver
Tips and Tricks
  1. Ensure good patient breath-holding for the heart and the liver scans by coaching as the scan duration is long
  2. Make sure the septum is of good image quality as this is where quantification is most reproducible
  3. Position the transverse liver slice correctly:
    • Avoid large hepatic vessels for correct T2* measurement in the liver tissue
ROIs are placed in the ventricular septum (A) and the liver (B)